Products Descriptions
CellGrow is a potent cell culture supplement designed to significantly enhance cell densities and maintain high viabilities in fed-batch and perfusion culture systems, leading to improved titres and reduced costs of goods.
Highlighted Product Characteristics:
- Achieves high cell densities.
- Maintains high cell viabilities.
- Extends fed-batch harvesting time.
- Improves product titers significantly.
- Reduces cost of goods (COGs).
- Suitable for fed-batch and perfusion cultures.
For Research Use Only. Not for use in diagnostics procedures, Not human or Animal use
Product Overview
CellGrow is a meticulously formulated cell culture supplement developed for biopharmaceutical manufacturers aiming to maximize recombinant protein and antibody production. In the demanding landscape of life science, achieving high product titers while maintaining cost-effectiveness is paramount. CellGrow addresses these critical needs by optimizing cell growth and longevity in large-scale cell culture systems.
This advanced supplement is engineered to provide essential nutrients and protective factors that support robust cell proliferation and survival, particularly in fed-batch and continuous perfusion culture methodologies. By providing a balanced and readily available source of key components, CellGrow empowers cells to reach exceptionally high densities, directly translating to increased volumetric productivity and enhanced overall yields.
Furthermore, CellGrow plays a crucial role in extending the productive lifespan of cell cultures. By mitigating cellular stress and maintaining high viability over extended culture periods, it allows for prolonged harvesting windows in fed-batch processes. This extended viability not only contributes to higher accumulated product but also offers greater flexibility in production scheduling.
The strategic use of CellGrow directly impacts the bottom line by significantly improving product titers, thereby reducing the required culture volumes and associated raw material consumption. This enhanced efficiency translates to substantial reductions in the cost of goods (COGs), making CellGrow a valuable tool for optimizing biomanufacturing economics.
Beyond its primary applications in fed-batch and perfusion cultures for recombinant protein production, CellGrow’s ability to support robust cell growth and viability may also benefit other cell culture applications where high cell numbers and prolonged culture times are desired, such as in the manufacturing of viral vectors, cell therapies, and other biologics. Its carefully selected components aim to create an optimal microenvironment for a wide range of mammalian cell lines commonly used in biopharmaceutical production, including but not limited to CHO, HEK293, and NS0 cells.
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| write to us if you have any further questions, our Technical Services team is ready to assist. |
Applications
- Recombinant Protein and Antibody Production (Fed-Batch Culture): CellGrow is specifically designed to boost cell density and extend viability in fed-batch cultures, leading to significantly higher yields of therapeutic proteins and monoclonal antibodies.
- Recombinant Protein and Antibody Production (Perfusion Culture): In continuous perfusion systems, CellGrow provides the necessary nutrients to sustain high cell densities and productivity over extended periods, maximizing output and process efficiency.
- Viral Vector Manufacturing: The robust growth and high viability supported by CellGrow can enhance the production of viral vectors used in gene therapy and vaccine development.
- Cell Therapy Manufacturing: For cell-based therapeutics, CellGrow can promote the expansion of therapeutic cells to the required numbers while maintaining their health and functionality.
- Troubleshooting Low Cell Density or Viability: When encountering suboptimal cell growth or declining viability in existing cell culture processes, incorporating CellGrow as a supplement can help to rescue and improve culture performance.
For Research Use Only. Not for use in diagnostics procedures, Not human or Animal use
How to Use It
Cellgrow is perfect for improving the growth of cell lines that have a tendency to grow slow in suspension culture. To determine the optimal dilution of Intraclone CellGrow for a specific cell line and process, a systematic Design of Experiments (DOE) approach is recommended. For more information, please refer to product Information brochure.
When to Add It: Add the reagent directly to your culture or during media preparation to boost cell growth
Need more information
| write to us if you have any further questions, our Technical Services team is ready to assist. |
